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KMID : 1024720160060010022
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Geriatric Rehabilitation
2016 Volume.6 No. 1 p.22 ~ p.26
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Vitamin D, K2 Supplementation on Osteoporosis Treatment
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Choi Hee-Eun
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Abstract
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The socioeconomic development and aging of the population of Korea have also raised interest in prevention and treatment of osteoporosis. Recently, extensive attention has been drawn to the effects of vitamin D and K2 supplementation on osteoporosis. Representative of osteoporosis medication is supply of calcium and vitamin D, use of inhibitors of bone resorption and bone formation accelerators. This review assessed the recent advance of vitamin D and K2 on osteoporosis treatment via an evidence-based approach. It is recommended that supplementation of both calcium and vitamin D is needed in the elderly and postmenopausal women. However continuing widespread use of vitamin D for osteoporosis prevention in community-dwelling adults without specific risk factors for vitamin D deficiency seems to be inappropriate. And currently there is not enough evidence to recommend the use of vitamin K2 supplements for the prevention of bone loss, fractures in postmenopausal women. Large well-designed randomized controlled trials are needed to establish the relevance of vitamin D alone and vitamin K2 status to such as bone mineral density and fracture.
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KEYWORD
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Osteoporosis, Vitamin D, Vitamin K2
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